Antidepressants

A class of antidepressants called selective serotonin reuptake inhibitors (SSRIs) are commonly used to treat depression. They work by changing your levels of serotonin — a neurotransmitter in the brain believed to be responsible for stabilizing your mood. Research indicates that SSRIs might help reduce the intensity and frequency of these autism-related behaviors: repetitive actions, anxiety, irritability, tantrums and aggressive actions. The SSRIs most commonly prescribed to autistic people are fluoxetine and sertraline. SSRIs can have significant side effects, such as: agitation, anxiety, diarrhea or constipation, weight change, dizziness, dry mouth, etc.

Parents and caregivers of autistic children are often concerned that the long-term effects of SSRIs have yet to be fully determined. There is no cure for autism spectrum disorder, but medications might help improve some behaviors related to the condition.