Nicotine Patch Therapy

Research studies have uncovered abnormalities in nicotinic acetylcholine receptors in the brains of people with autism, and some scientists have posited that core symptoms of autism could be attributed to these alterations. Some findings specifically indicate a shortage of these receptors, leading some to believe that stimulating or increasing these receptors could eliminate autism symptoms. Proponents of nicotine patch use in individuals with autism believe that the nicotine released into the body from the patch activates and upregulates receptors, and thereby reduces autism symptoms. Despite having a rationale that is based on scientific findings, use of this treatment is not supported by scientific evidence. No clinical trials have demonstrated that nicotine patches are safe or effective in the treatment of ASD. Common side effects reported in clinical studies evaluating safety and efficacy of the patches include skin irritation; sleep problems, including insomnia and nightmares; headaches, indigestion, and nervousness.