Antihistamines

The use of antihistamines for treating autism is an area that has not been extensively studied, and there is limited evidence to support their efficacy for managing core symptoms of autism. Antihistamines are primarily used to treat allergic reactions, insomnia, and sometimes anxiety due to their sedative effects. There is no substantial clinical evidence to support the routine use of antihistamines for treating autism. The few studies that exist are often small and lack rigorous controls.

Antihistamines can cause side effects, including drowsiness, dizziness, dry mouth, and, in some cases, paradoxical excitement (increased activity rather than sedation).

Regular use of sedative antihistamines can lead to tolerance, meaning that over time, higher doses may be needed to achieve the same effect. There is also a risk of dependency.

Antihistamines do not address the core symptoms of autism, such as communication difficulties, social challenges, and repetitive behaviors. Their use is generally aimed at secondary issues like sleep problems or anxiety.