Autherapies | Evidence-based therapies

Probiotics

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Probiotics, which are live microorganisms that promote gut health, have gained attention as a potential intervention for autism spectrum disorder (ASD). The "gut-brain axis" concept, suggesting a link between gut health and brain function, has spurred interest in using probiotics to alleviate some autism symptoms. However, the scientific evidence supporting probiotics as a treatment for autism is still in its early stages, and parents should approach this intervention with caution. Probiotics are live bacteria and yeasts that are thought to improve or restore gut flora balance. Common strains include Lactobacillus and Bifidobacterium. Probiotics can be consumed through supplements or in fermented foods like yogurt, kefir, sauerkraut, and kombucha. The rationale behind using probiotics for autism stems from the idea that improving gut health may positively influence behavior and cognitive function via the gut-brain axis, a communication network between the gastrointestinal tract and the central nervous system. Some small studies and animal models suggest that probiotics may help with gastrointestinal symptoms in children with autism, which could, in turn, reduce irritability and improve behavior. However, these studies are often limited in scope and methodology, and many have not been replicated in larger, more rigorous trials. There are some reports that probiotics could improve social communication, reduce repetitive behaviors, and lower anxiety in children with autism. However, the evidence is inconsistent, and most studies show only modest improvements in behavior, if any.

The most consistent finding is that probiotics can improve gastrointestinal issues like constipation or diarrhea in some children with autism. While this might indirectly improve mood or behavior, the direct impact on core autism symptoms remains unclear. Probiotics are generally considered safe for most people, including children, but they are not without risks. In rare cases, probiotics can cause infections, particularly in individuals with weakened immune systems.

Probiotic supplements are not regulated as strictly as medications, so the quality and potency can vary widely between products. Some supplements may not contain the strains they claim or may have lower levels of live bacteria than advertised. Before starting probiotics, parents should consult with a healthcare provider, especially if their child has underlying health conditions or is on medications. A doctor can recommend the appropriate strain and dosage, and monitor for any potential side effects.

References

The impact of probiotics on core autism symptoms - A systematic review and meta-analysis of randomized clinical trials

Link Source

https://pubmed.ncbi.nlm.nih.gov/39173907/


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