Autherapies | Evidence-based therapies

Immune globulin

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Immune globulin therapy (also known as intravenous immune globulin, or IVIG) is a treatment typically used to manage immune system disorders. Given the emerging theories that autism spectrum disorder (ASD) might involve immune dysfunction or inflammation, some have proposed IVIG as a potential treatment for autism. However, the evidence for its effectiveness in autism is extremely limited, and there are significant risks associated with its use. Research on the use of IVIG in autism is extremely limited, with only a few small, poorly controlled studies and case reports. These studies do not provide strong evidence that IVIG is an effective treatment for autism. IVIG is a powerful therapy that comes with significant risks, including allergic reactions, blood clots, kidney damage, and infections. It is not a treatment to be used lightly, especially in children who may not need it.

IVIG is a costly treatment, often running into thousands of dollars per infusion. It is usually reserved for individuals with serious immune deficiencies or autoimmune disorders, and its use for autism is considered experimental. IVIG is not without significant risks, including life-threatening side effects. Parents should be fully informed about these risks before considering this treatment for their child with autism. The potential for harm often outweighs the unclear and unproven benefits in this context. Some practitioners may offer IVIG as a treatment for autism without sufficient scientific backing. Parents should be cautious of unregulated or "alternative" clinics that make exaggerated claims about the benefits of IVIG for autism. Always seek treatments from licensed medical professionals who follow evidence-based practices.

References

Guidelines on the use of intravenous immune globulin for neurologic conditions

Link Source

https://pubmed.ncbi.nlm.nih.gov/17397768/


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