Coimbra protocol

The Coimbra Protocol is a treatment regimen that involves high-dose vitamin D and other supplements, initially developed for autoimmune conditions and more recently explored for various disorders, including autism. Proponents of the Coimbra Protocol claim that high-dose vitamin D and a tailored supplement regimen can help improve cognitive function and other symptoms in autism. However, the scientific evidence supporting the Coimbra Protocol specifically for autism is limited, and parents should approach it with caution. Based on the idea that Autism is an auto-immune disorder, it prescribes vitamin D supplements that range from 40000 to 200000 IU daily, even though the safe upper limit of intake is set at 4,000 IU per day. As of now, there is limited scientific research specifically addressing the effectiveness of the Coimbra Protocol for autism. Most research on high-dose vitamin D focuses on autoimmune diseases or general health rather than autism. High doses of vitamin D can lead to toxicity, causing hypercalcemia (elevated calcium levels), which can result in kidney damage, cardiovascular issues, and other health problems. The safety of high-dose vitamin D, especially in children, requires careful management and monitoring. Excessive intake of vitamin D can be harmful, leading to potential side effects such as nausea, vomiting, weakness, and serious complications like kidney stones and bone pain. High-dose vitamin D might interact with other medications or treatments, potentially affecting their efficacy or causing adverse effects. The Coimbra Protocol may vary in its application and adherence, leading to inconsistencies in dosage and effectiveness. Without standardized guidelines and robust evidence, results can be unpredictable.