Autherapies | Evidence-based therapies

Loperamide

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Loperamide is an over-the-counter medication primarily used to treat diarrhea by slowing down bowel movements. It is sometimes discussed in the context of autism because children with autism often experience gastrointestinal (GI) issues, such as diarrhea or constipation. While loperamide can manage diarrhea in general, there is no scientific evidence to support its use as a treatment for autism or its core symptoms. Many children with autism experience GI problems, such as diarrhea, constipation, bloating, or food sensitivities. GI issues can exacerbate behavioral symptoms like irritability, anxiety, and discomfort, leading some parents to seek treatments like loperamide for relief. Although loperamide can help manage diarrhea, it does not address the underlying causes of GI issues in children with autism, which may be related to gut-brain interactions, food intolerances, or sensory processing difficulties. Loperamide can cause constipation if used for extended periods, which may exacerbate GI issues rather than relieve them. In some cases, loperamide may cause drowsiness, dizziness, or stomach pain.

References

Drug repurposing candidates to treat core symptoms in autism spectrum disorder

Link Source

https://pubmed.ncbi.nlm.nih.gov/36172193/


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